L-Asparaginase 10000IU Injection In Pakistan

L-Asparaginase 10,000 IU Injection is an anticancer medicine containing the enzyme L-asparaginase. It is used as part of combination chemotherapy for the treatment of acute lymphoblastic leukaemia (ALL), a type of blood cancer.

L-Asparaginase works by reducing the amount of asparagine in the blood. Certain leukaemia cells depend on this amino acid for their growth and survival. By reducing its availability, the medicine helps inhibit the growth of these cancer cells.

It is a specialised chemotherapy medicine that must be administered under the supervision of an experienced oncologist or qualified healthcare professional.

Product Information

Manufacturer, pack size, approved route and excipients should be confirmed from the actual product packaging.

Uses and Indications

L-Asparaginase 10,000 IU Injection is primarily used as part of combination chemotherapy for:

• Acute lymphoblastic leukaemia (ALL).

• Certain lymphoblastic leukaemia treatment protocols.

• Selected patients receiving specialist-directed chemotherapy regimens.

The medicine is generally combined with other anticancer medicines according to an established treatment protocol.

How Does L-Asparaginase Work?

L-Asparaginase is an enzyme that breaks down the amino acid asparagine into aspartic acid and ammonia.

Some leukaemia cells cannot produce sufficient asparagine themselves and depend on the supply available in the bloodstream. By reducing circulating asparagine, L-Asparaginase can interfere with the growth and survival of these cancer cells.

Dosage and Administration

• The dose is determined by the treating oncologist.

• Dosage depends on the patient's age, body weight, treatment protocol and clinical condition.

• The powder must be reconstituted according to the specific manufacturer's instructions.

• Administration may be intravenous or intramuscular for certain conventional formulations; the approved route must be checked on the supplied product label.

• Patients require appropriate monitoring during and after treatment.

Important: 10,000 IU represents the total strength of the vial, not an individual patient's prescribed dose. Do not prepare or administer this medicine without professional supervision.

Possible Side Effects

L-Asparaginase may cause side effects, including:

• Nausea and vomiting.

• Allergic reactions and skin rash.

• Fever and chills.

• Increased blood glucose levels.

• Abnormal liver function.

• Pancreatitis.

• Changes in blood clotting.

• Increased risk of bleeding or blood clots.

• Reduced blood cell counts.

• Elevated blood lipids.

Serious allergic reactions, including anaphylaxis, can occur. Immediate medical attention is required if breathing difficulty, facial swelling, severe abdominal pain or signs of a serious reaction develop.

Warnings and Precautions

Before starting treatment, the healthcare professional should review the patient's medical history and current medicines.

Important precautions include:

• Allergic reactions: Patients should be monitored for hypersensitivity and anaphylaxis.

• Pancreatitis: Previous or current pancreatitis requires careful specialist assessment.

• Blood clots: L-Asparaginase can increase the risk of thrombosis.

• Bleeding: Changes in clotting factors may increase bleeding risk.

• Liver function: Liver function should be monitored during treatment.

• Blood glucose: Hyperglycaemia may occur, so glucose monitoring may be necessary.

• Pregnancy and breastfeeding: Treatment requires specialist assessment because of potential risks.

Treatment should take place in a hospital or specialist oncology setting with facilities available to manage serious adverse reactions.

Storage Instructions

• Store refrigerated at 2°C to 8°C.

• Do not freeze.

• Protect the vial from direct light.

• Keep the medicine in its original packaging.

• Follow the manufacturer's instructions for reconstitution.

• Use the prepared solution within the specified period.

• Do not use damaged, expired or improperly stored vials.

Always follow the storage and handling instructions supplied with the exact brand.

L-Asparaginase 10,000 IU Injection Price in Pakistan

The price of L-Asparaginase 10,000 IU Injection in Pakistan may vary depending on the manufacturer, brand, import status and availability.

For the latest price and stock information, contact 1

Buy L-Asparaginase 10,000 IU Injection in Pakistan

Looking for L-Asparaginase 10,000 IU Injection in Pakistan? Contact Onlinetrade.pk for product details, pricing and availability.

Before purchasing, verify the manufacturer's name, batch number, expiry date, product authenticity and cold-chain storage history. This is a specialised chemotherapy medicine and should only be used under an oncologist's supervision.

Available Across Pakistan

Customers can contact Onlinetrade.pk for availability and delivery information in:

Lahore, Karachi, Islamabad, Bahawalpur, Peshawar, Multan, Gujranwala, Rawalpindi, Hyderabad, Faisalabad, Larkana, Sukkur, Sialkot and all other major cities of Pakistan.

Stock and delivery arrangements should be confirmed before ordering.

Frequently Asked Questions (FAQs)

1. What is L-Asparaginase 10,000 IU Injection used for?

It is primarily used as part of combination chemotherapy for acute lymphoblastic leukaemia (ALL).

2. What is the strength of this injection?

Each stated vial contains 10,000 International Units (IU) of L-Asparaginase.

3. How does L-Asparaginase work?

It reduces the availability of asparagine in the bloodstream, which can help inhibit the growth of certain leukaemia cells.

4. Does L-Asparaginase require refrigeration?

Yes. It is generally stored at 2°C to 8°C and must not be frozen. Follow the specific product label.

5. Can L-Asparaginase be administered at home?

No. It requires specialist supervision and appropriate facilities to manage potentially serious allergic and other adverse reactions.

6. Is L-Asparaginase used alone?

It is generally used as part of a combination chemotherapy regimen prescribed by an oncologist.