Icikinase (Recombinant Streptokinase for Injection I.P. 1500000IU) In Pakistan

Icikinase 1,500,000 IU Injection is a thrombolytic medicine containing recombinant streptokinase. It is used in selected medical emergencies to help dissolve blood clots and restore blood circulation in blocked blood vessels.

Streptokinase works by activating plasminogen, a naturally occurring protein in the blood, into plasmin. Plasmin helps break down fibrin, the protein structure that holds blood clots together.

Icikinase is a specialised hospital-use medicine that requires immediate medical assessment and administration by qualified healthcare professionals.

Product Information

Uses and Indications

Icikinase may be prescribed by specialists for selected conditions involving dangerous blood clots, including:

• Acute Myocardial Infarction: Used in selected heart attack patients to help dissolve blood clots obstructing coronary arteries.

• Pulmonary Embolism: May be used in selected patients with serious blood clots in the lungs.

• Deep Vein Thrombosis (DVT): May be considered in selected cases involving blood clots in deep veins.

• Arterial Thrombosis: May help restore blood flow in certain blocked arteries.

• Thromboembolic Conditions: Used in specialist-directed treatment protocols when thrombolytic therapy is appropriate.

The choice of thrombolytic treatment depends on the patient's condition, timing, bleeding risk and available treatment alternatives.

How Does Icikinase Work?

Icikinase contains streptokinase, which forms an activating complex with plasminogen in the blood.

This complex converts plasminogen into plasmin. Plasmin breaks down fibrin, the protein network responsible for holding blood clots together.

By promoting clot breakdown, streptokinase can help restore blood flow through affected blood vessels.

Dosage and Administration

• Administer only in a hospital or appropriate emergency-care setting.

• The medicine is administered intravenously according to the prescribed treatment protocol.

• The vial must be reconstituted using the specified sterile solution and manufacturer's instructions.

• The prescribed dose and infusion duration depend on the medical indication and patient's condition.

• Patients require close monitoring of blood pressure, bleeding symptoms and relevant laboratory parameters.

• Do not administer without a specialist's prescription and supervision.

Important: 1,500,000 IU represents the total strength of the vial, not an instruction for every patient to receive that amount. Thrombolytic treatment is time-sensitive and carries a significant risk of serious bleeding.

Possible Side Effects

Possible side effects of streptokinase include:

• Bleeding or bruising.

• Low blood pressure (hypotension).

• Fever and chills.

• Nausea or vomiting.

• Allergic reactions.

• Skin rash or itching.

• Irregular heartbeat.

• Injection or infusion-related reactions.

Serious complications may include internal bleeding, gastrointestinal bleeding, intracranial haemorrhage and severe allergic reactions, including anaphylaxis. Immediate medical attention is required if serious symptoms develop.

Warnings and Precautions

Before treatment, the medical team must carefully assess the patient's medical history and bleeding risk.

Important precautions include:

• Active bleeding: Streptokinase should not be used in patients with active internal bleeding.

• Previous stroke: Recent stroke or intracranial bleeding can make treatment dangerous.

• Recent surgery or trauma: These may significantly increase the risk of severe bleeding.

• Uncontrolled hypertension: High blood pressure can increase the risk of intracranial haemorrhage.

• Previous streptokinase treatment: Previous exposure may increase the risk of allergic reactions and reduce treatment effectiveness because of antibodies.

• Pregnancy: Use requires careful specialist assessment.

• Anticoagulants and antiplatelets: Medicines such as heparin, warfarin and aspirin may increase bleeding risk when used with thrombolytic treatment.

The treating physician must assess contraindications and potential drug interactions before administration.

Storage Instructions

• Follow the storage conditions printed on the Icikinase packaging.

• Protect the vial from direct sunlight and excessive heat.

• Do not freeze unless the manufacturer's instructions specifically permit it.

• Keep the medicine in its original packaging.

• Reconstitute only according to the supplied product instructions.

• Check the expiry date and vial integrity before use.

Storage requirements can vary between manufacturers, so always follow the official Icikinase product leaflet.

Icikinase 1,500,000 IU Injection Price in Pakistan

The price of Icikinase Recombinant Streptokinase 1,500,000 IU Injection in Pakistan may vary depending on the supplier, manufacturer, import status and availability.

For the latest price and stock information, contact Onlinetrade.pk.

Buy Icikinase 1,500,000 IU Injection in Pakistan

Looking for Icikinase Recombinant Streptokinase for Injection I.P. 1,500,000 IU in Pakistan?

Contact Onlinetrade.pk for product information, current pricing and availability.

Before purchasing, verify the manufacturer's details, product authenticity, batch number, expiry date and storage history. This is a high-risk emergency medicine and must only be administered by qualified healthcare professionals.

Available Across Pakistan

Customers can contact Onlinetrade.pk for availability and delivery information in:

Lahore, Karachi, Islamabad, Bahawalpur, Peshawar, Multan, Gujranwala, Rawalpindi, Hyderabad, Faisalabad, Larkana, Sukkur, Sialkot and all other major cities of Pakistan.

Stock availability and delivery arrangements should be confirmed before ordering.

Frequently Asked Questions (FAQs)

1. What is Icikinase 1,500,000 IU Injection used for?

Icikinase is a thrombolytic medicine used in selected conditions involving serious blood clots, including certain cases of acute myocardial infarction and pulmonary embolism.

2. What is the active ingredient in Icikinase?

It contains recombinant streptokinase, a thrombolytic agent that helps break down blood clots.

3. What is the strength of Icikinase Injection?

Each stated vial contains 1,500,000 International Units (IU) of recombinant streptokinase.

4. How is Icikinase administered?

It is administered intravenously under specialist supervision in an appropriate medical setting.

5. Is Icikinase an anticoagulant?

No. It is a thrombolytic medicine. Unlike anticoagulants, which help prevent clot formation or extension, thrombolytics help dissolve existing blood clots.

6. Can Icikinase be used without medical supervision?

No. It can cause life-threatening bleeding and requires hospital-based medical assessment and monitoring.