Arsenic Trioxide Injection 10mg/10mL In Pakistan

Arsenic Trioxide Injection 10mg/10mL is a prescription anticancer medicine used primarily in the treatment of acute promyelocytic leukemia (APL), a specific type of acute myeloid leukemia. It contains arsenic trioxide as its active ingredient and is administered intravenously under the supervision of a qualified hematologist or oncologist.

Active Ingredient

• Generic Name: Arsenic Trioxide

• Strength: 10 mg/10 mL

• Concentration: 1 mg/mL

• Dosage Form: Injection

• Route of Administration: Intravenous infusion

• Therapeutic Class: Antineoplastic agent

• Drug Class: Arsenical compound

Uses & Indications

Arsenic Trioxide Injection is primarily used for the treatment of acute promyelocytic leukemia (APL), including:

• Newly diagnosed low-risk APL in combination with other prescribed treatment.

• Relapsed or refractory APL in selected patients.

• APL that has not responded adequately to previous treatment.

• APL that has returned following earlier chemotherapy or other treatment.

The exact treatment plan depends on the patient's diagnosis, disease status, previous treatments, and overall medical condition.

How Does Arsenic Trioxide Work?

Arsenic trioxide works by promoting the breakdown of the abnormal PML-RARα fusion protein associated with acute promyelocytic leukemia. It helps trigger differentiation and programmed cell death (apoptosis) in abnormal leukemia cells.

This mechanism helps reduce the number of cancerous cells and supports the treatment of APL.

Dosage & Administration

Arsenic Trioxide Injection should be administered only by qualified healthcare professionals under the supervision of a hematologist or oncologist.

The dosage and treatment schedule depend on:

• Patient's body weight

• Type and stage of leukemia

• Previous treatment history

• Overall health condition

• Response to treatment

• Prescribed chemotherapy protocol

It is generally administered as a controlled intravenous infusion. Regular laboratory testing and cardiac monitoring are important during treatment.

Important Precautions

Before and during treatment, healthcare professionals should monitor:

• Electrocardiogram (ECG)

• QT interval and heart rhythm

• Potassium levels

• Magnesium levels

• Liver function

• Kidney function

• Complete blood count

• Signs of differentiation syndrome

Arsenic trioxide can cause serious heart rhythm abnormalities and differentiation syndrome. Patients require careful medical supervision throughout treatment.

Possible Side Effects

Possible side effects of Arsenic Trioxide Injection may include:

• Nausea and vomiting

• Fatigue

• Headache

• Fever

• Diarrhea

• Abdominal discomfort

• Swelling or fluid retention

• Changes in liver function

• Electrolyte abnormalities

• Prolonged QT interval

• Cardiac arrhythmias

• Differentiation syndrome

Seek immediate medical attention if symptoms such as breathing difficulties, sudden weight gain, swelling, chest discomfort, irregular heartbeat, or severe fever develop.

Storage

Store Arsenic Trioxide Injection according to the manufacturer's instructions and approved product labeling. Keep the medicine in its original packaging and protect it from unsuitable storage conditions.

The injection should be handled and prepared by trained healthcare professionals using appropriate precautions. Do not use the product if the vial or packaging is damaged.

Arsenic Trioxide Injection 10mg/10mL Price in Pakistan

The price of Arsenic Trioxide Injection 10mg/10mL in Pakistan may vary depending on the manufacturer, brand, supplier, packaging, and market availability.

For the latest price and availability, customers can contact Onlinetrade.pk.

Buy Arsenic Trioxide Injection 10mg/10mL in Pakistan

Looking to buy Arsenic Trioxide Injection 10mg/10mL in Pakistan? Onlinetrade.pk provides an online platform for pharmaceutical product enquiries and availability information.

Customers should confirm the manufacturer, brand, batch details, expiry date, stock availability, pricing, and delivery arrangements before placing an order.

Arsenic Trioxide is a prescription anticancer medicine and should only be prescribed and administered under the supervision of a qualified hematologist or oncologist.

Arsenic Trioxide Injection Availability Across Pakistan

Arsenic Trioxide Injection may be available for customers in:

Lahore, Karachi, Islamabad, Bahawalpur, Peshawar, Multan, Gujranwala, Rawalpindi, Hyderabad, Faisalabad, Larkana, Sukkur, Sialkot, Rahim Yar Khan, and all other major cities across Pakistan, subject to stock availability.

Contact Onlinetrade.pk to confirm current stock and delivery information for your city.