Altuzan 400mg /16ml Bevacizumab Injection In Pakistan

Altuzan 400mg/16ml Injection contains bevacizumab, a monoclonal antibody used in the treatment of certain types of cancer. It works by blocking vascular endothelial growth factor (VEGF), a protein that helps tumors develop new blood vessels.

By inhibiting VEGF, bevacizumab can reduce the formation of new blood vessels that supply tumors. It is used in combination with other cancer treatments for specific indications under the supervision of an oncologist.

Product Information

• Brand Name: Altuzan

• Generic Name: Bevacizumab

• Strength: 400mg/16ml

• Concentration: 25mg/ml

• Dosage Form: Concentrate for solution for infusion

• Drug Class: Antineoplastic agent; VEGF inhibitor

• Route of Administration: Intravenous infusion

• Availability in Pakistan: Subject to local registration, supplier stock, and pharmacy availability.

Medical Uses of Altuzan Injection

Altuzan may be prescribed as part of combination therapy for certain cancers, including:

• Metastatic colorectal cancer

• Non-small cell lung cancer

• Certain types of ovarian, fallopian tube, or peritoneal cancer

• Cervical cancer

• Selected cases of kidney cancer and other approved indications

The exact indication depends on the cancer type, stage, and applicable treatment protocol.

How Does Bevacizumab Work?

Bevacizumab targets VEGF, a protein involved in the growth of new blood vessels. By blocking this protein, it helps limit the blood supply that tumors need to grow. It is generally used alongside other anticancer medicines when clinically indicated.

Dosage and Administration

• Administered through intravenous infusion.

• The dose is calculated according to the patient's body weight and specific treatment regimen.

• Infusion timing and frequency depend on the cancer being treated.

• It must be administered by trained healthcare professionals under an oncologist's supervision.

Important: Bevacizumab is not suitable for self-administration.

Possible Side Effects

Potential side effects include:

• High blood pressure

• Nosebleeds and other bleeding

• Protein in the urine

• Delayed wound healing

• Increased risk of blood clots

• Gastrointestinal perforation in rare but serious cases

Seek urgent medical attention for severe abdominal pain, significant bleeding, chest pain, or sudden neurological symptoms.

Precautions and Warnings

Before treatment, inform the oncologist about any history of high blood pressure, bleeding disorders, blood clots, recent surgery, or kidney problems. Bevacizumab can increase the risk of serious bleeding and impaired wound healing. Treatment timing around surgery requires careful medical assessment.