Azacitidine for Injection 100mg Lyophilized Powder In Pakistan

Azacitidine for Injection 100mg is a prescription anticancer chemotherapy medicine supplied as a sterile, lyophilized powder in a single-dose vial. Azacitidine belongs to the class of antimetabolite and pyrimidine analogue medicines and is used in the management of certain blood cancers and bone-marrow disorders. 

Product Details

• Generic Name: Azacitidine
• Strength: 100mg
• Dosage Form: Lyophilized Powder for Injection
• Pack: 100mg single-dose vial
• Routes: Subcutaneous or intravenous administration, depending on the prescribed formulation and treatment protocol
• Category: Antineoplastic / Chemotherapy
• Prescription: Prescription-only medicine
• Active Ingredient: Azacitidine 100mg 

What Is Azacitidine 100mg Used For?

Azacitidine is primarily used in the treatment of certain myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) in appropriate patients. It works as a cytidine nucleoside analogue and has both hypomethylating and cytotoxic effects on abnormal hematopoietic cells. 

How Does Azacitidine Work?

Azacitidine can interfere with abnormal DNA methylation and affect the growth and survival of abnormal blood-forming cells. This mechanism may help restore more normal cellular activity and reduce the proliferation of malignant cells. 

Administration

Azacitidine 100mg must be reconstituted and administered by trained healthcare professionals according to the prescribed treatment protocol. Depending on the product and route, it may be administered subcutaneously or intravenously. The FDA labeling specifies a 100mg lyophilized powder in a single-dose vial.

Do not self-administer this medicine.

Common Side Effects

Possible side effects may include:

• Nausea and vomiting
• Fatigue and weakness
• Fever
• Diarrhea or constipation
• Injection-site reactions
• Anemia
• Neutropenia
• Thrombocytopenia
• Reduced appetite

Azacitidine can significantly reduce blood-cell counts, so regular blood-count monitoring is important during treatment. 

Important Precautions

Azacitidine is a cytotoxic chemotherapy medicine and requires appropriate handling, preparation, administration, and disposal procedures. Patients with liver or kidney problems should inform their treating physician before treatment. 

Azacitidine injection should not be substituted with oral azacitidine on a dose-for-dose basis, because the products have substantially different pharmacokinetic properties and dosing schedules. 

Storage

Unreconstituted azacitidine injection is generally stored at controlled room temperature, according to the specific manufacturer's labeling. The exact storage requirements should always be checked on the product packaging and manufacturer's instructions. 

Available at Onlinetrade.pk

Azacitidine for Injection 100mg Lyophilized Powder is available through Onlinetrade.pk in Pakistan, subject to current stock and product availability.

It can be supplied to customers in major cities of Pakistan, including Lahore, Karachi, Islamabad, Rawalpindi, Multan, Faisalabad, Peshawar, Gujranwala, Sialkot, Hyderabad, Bahawalpur, Sukkur, Larkana and other areas.