Resicov Leucovorin Calcium Injection IP 50mg/5.5mL In Pakistan

Resicov Leucovorin Calcium Injection IP 50mg/5.5mL is a prescription medicine containing Leucovorin Calcium, also known as Folinic Acid. It is a reduced form of folic acid used in specific medical treatments, particularly to reduce the toxic effects of certain chemotherapy medicines such as methotrexate. It may also be used in combination with fluorouracil (5-FU) for the treatment of certain types of cancer.

Resicov is administered under the supervision of a qualified healthcare professional according to the prescribed treatment protocol.

Composition

• Brand Name: Resicov

• Active Ingredient: Leucovorin Calcium

• Alternative Name: Folinic Acid

• Strength: 50mg/5.5mL

• Dosage Form: Injection

• Pharmacopoeia: IP (Indian Pharmacopoeia)

• Drug Category: Folinic Acid / Folate Derivative

• Route of Administration: Intravenous or intramuscular, depending on the prescribed indication and product instructions

Uses of Resicov Leucovorin Calcium Injection

Leucovorin Calcium is used for several medical purposes, including:

• Methotrexate Rescue: Helps reduce the harmful effects of high-dose methotrexate chemotherapy on normal cells.

• Cancer Treatment: Used in combination with fluorouracil (5-FU) for certain colorectal cancer treatment regimens.

• Folate Deficiency: Used in selected cases of folate deficiency when folinic acid treatment is appropriate.

• Medication Toxicity: May be used in specific cases of folic acid antagonist toxicity, according to medical guidance.

The exact use depends on the patient's diagnosis and prescribed treatment protocol.

How Leucovorin Calcium Works

Leucovorin Calcium is a reduced form of folic acid. Unlike ordinary folic acid, it does not require activation by the enzyme dihydrofolate reductase.

It helps restore folate-dependent processes in normal cells affected by medicines such as methotrexate. When used with fluorouracil, it enhances the binding of fluorouracil's active metabolite to thymidylate synthase, increasing its anticancer activity.

Dosage and Administration

The dosage of Resicov depends on the medical condition, chemotherapy regimen, methotrexate levels when applicable, kidney function, and patient's clinical response.

• Administered by a qualified healthcare professional.

• May be given intravenously or intramuscularly, depending on the indication and product labeling.

• Dosage and timing are determined by the treating physician.

• During methotrexate rescue, treatment timing and dose adjustments may depend on blood methotrexate levels and kidney function.

• Regular laboratory monitoring may be required.

Important: Do not self-administer Resicov Injection. Follow the treating physician's instructions carefully, especially when it is used as part of chemotherapy.

Possible Side Effects

Leucovorin Calcium is generally well tolerated, but some patients may experience:

• Nausea and vomiting

• Diarrhea

• Skin rash

• Allergic reactions

• Fever

• Injection-site discomfort

When used with fluorouracil, it may increase certain chemotherapy-related side effects, including diarrhea, mouth sores, and bone marrow suppression.

Important Precautions

Before receiving Resicov, inform your healthcare provider about existing medical conditions, allergies, and all medicines being taken.

Important precautions include:

• Inform your doctor if you have a history of seizures or epilepsy.

• Monitor blood counts when used in chemotherapy regimens.

• Follow methotrexate monitoring and rescue schedules carefully.

• Monitor for gastrointestinal toxicity when combined with fluorouracil.

• Use caution in patients with vitamin B12 deficiency.

Leucovorin is not a substitute for vitamin B12 treatment in patients with vitamin B12 deficiency.

Storage

Store Resicov Leucovorin Calcium Injection according to the manufacturer's recommended storage conditions and approved product labeling. Protect the product from unsuitable temperatures and light where specified. Follow the manufacturer's instructions for handling and storage after opening or preparation.

Keep out of reach of children.

Resicov Leucovorin Calcium Injection IP 50mg/5.5mL In Pakistan

Resicov Leucovorin Calcium Injection IP 50mg/5.5mL is available at Onlinetrade.pk in Pakistan, subject to current stock and applicable prescription requirements.

Customers and healthcare professionals can contact Onlinetrade.pk for product availability and ordering information.

Availability in Pakistan

Resicov Leucovorin Calcium Injection may be available in major cities of Pakistan, including Lahore, Karachi, Islamabad, Rawalpindi, Multan, Faisalabad, Peshawar, Gujranwala, Hyderabad, Bahawalpur, Sialkot, Sukkur, Larkana, and other major cities, subject to stock availability.

Frequently Asked Questions (FAQs)

What is Resicov Leucovorin Calcium Injection used for?

It is used to reduce the toxic effects of certain folate-antagonist medicines, particularly methotrexate, and in combination with fluorouracil for selected cancer treatments.

What is the strength of Resicov Injection?

Resicov contains 50mg of Leucovorin Calcium in a 5.5mL injection.

Is Leucovorin Calcium the same as folic acid?

No. Leucovorin is a reduced form of folic acid known as folinic acid. It can be used in specific medical situations where ordinary folic acid is not suitable.

How is Resicov administered?

Depending on the indication and product instructions, it may be administered intravenously or intramuscularly by a qualified healthcare professional.

Can Resicov be used with chemotherapy?

Yes. It is commonly used in methotrexate rescue protocols and may be combined with fluorouracil in certain cancer treatment regimens.

Where can I find Resicov Injection in Pakistan?

You can check its availability at Onlinetrade.pk, subject to current stock and prescription requirements.